Sorry, your blog cannot share posts by email. My protocol is here: He is an internationally recognised Clinician Educator with a passion for helping clinicians learn and for improving the clinical performance of individuals and collectives. 2010 Mar;17(3):297-306. The search had been completed, and 2 new trials had been found (including Lim), which did not change the overall conclusions of the review. . We occasionally have to perform painful procedures on patients who are not fully sedated or adequately analgesed. 2009. These papers suggests that the ILCOR recommendations are wrong. I was taught that, for a variety of reasons, it’s an awful drug. PMID: 19261367, Should we use TXA for traumatic brain injury? dilzem is a better choice because of availibility in primary care . They have been described as awful by every patient I have treated, and the doctors who have commented on this post through Facebook and twitter provide similar stories. Chris is an Intensivist and ECMO specialist at the Alfred ICU in Melbourne. Having said this – the data is compelling enough to try CCBs for a future encounter. Resuscitation. FOAM enthusiast. I believe that if you tell patients it is going to be ‘awful’ or ‘a horrible feeling’ their perception maybe different than if you say ‘unusual feeling, weird feeling or flushed’. But what about the 2010 ILCOR guidelines? The calcium channel blockers were better than adenosine at converting patients back to sinus rhythm (98% vs 86.5%, p=0.002, RR 1.13, 95% CI 1.04-1.23). Adenosine is also used during a stress test of the heart. There were more adverse events with adenosine (10.8% vs 0.6%, p<0.001, OR 0.15, 95% CI 0.09 to 0.26). Your colleague says he thinks it is an SVT with aberrant conduction because the patient is young, haemodynamically stable and has no history of heart disease. propofol IV) prior to electrical cardioversion (e.g. J Electrocardiol. There are clearly patients in whom the risk of hypotension outweighs the problem of momentary pain and suffering. These symptoms came on while he was running on a treadmill at his local gym. 2010 Nov 2;122(18 Suppl 3):S729-67. ABLATION may well be an option if BETA BLOCKERS do not succeed. no significant adverse events in my case series at doses of 1-4 mg of midaz prior to conversion w adenosine. Adenosine may help distinguish atrial flutter from SVT, but adenosine is not effective for atrial flutter, atrial fibrillation, or tachycardia that is not caused by AV nodal reentry. However, it is not dangerous to use adenosine in this setting — it just can’t be relied upon to make the diagnosis. They identified 8 RCTs comparing adenosine to calcium channel blockers. Adenosine can revert VT… and won’t revert all cases of SVT with (or without) aberrancy. Calcium channel blockers are not the ideal first line agent for patients in cardiogenic shock. (This is not like the, Click to share on Twitter (Opens in new window), Click to share on Facebook (Opens in new window), Click to share on LinkedIn (Opens in new window), Click to share on Reddit (Opens in new window), Click to share on Pocket (Opens in new window), Click to email this to a friend (Opens in new window), Click to share on WhatsApp (Opens in new window), Click to share on Tumblr (Opens in new window), […] grand merci à Dr. Justin Morgenstern et son post sur First10em.com pour l’inspiration, et a Dani Sanchis pour son […], […] My practice is that in patients with stable SVT, my go to move would be modified Valsalva maneuver, which…, […] Adenosine is what most people are perhaps the most comfortable with given its historical use – but, it makes…, TXA in traumatic brain injury – a quick update, http://broomedocs.com/2015/12/clinical-case-123-svt-better/. Adenosine has a rapid onset and a half-life that is <10 seconds, which makes it an ideal agent for hemodynamically stable SVT. PMID. I really think so, but there is also an important patient safety consideration. By 30 minutes, blood pressure had returned to pretreatment levels. He coordinates the Alfred ICU’s education and simulation programmes and runs the unit’s education website, INTENSIVE. Acad Emerg Med. He is on the Board of Directors for the Intensive Care Foundation and is a First Part Examiner for the College of Intensive Care Medicine. | INTENSIVE | RAGE | Resuscitology | SMACC. The advantage of being very fast and not causing hypotension. All that silly stuff we just did – getting you to blow in a syringe and raising your legs above your head – that sometimes works, but honestly, I have never seen it work myself. My first step here would be to simply cardiovert the patient out of SVT. It’s time to stop asking you to “bear down” and move on to using medications to slow your heart down. Amiodarone or procainamide for the termination of sustained stable ventricular tachycardia: an historical multicenter comparison. I am not calling for an outright ban on adenosine. Provide your patients with adequate procedural sedation. Have had many patients tell me how much better an experience it was as compared to Adenosine. (The authors classify these as minor, but minor is not a word I have ever heard from a patient given adenosine). Review. Your colleague suggests, citing the 2010 ILCOR guidelines, that adenosine could be administered and if the patient reverts then the diagnosis of SVT with aberrancy will be confirmed. If our patients were aware, I think they might revolt. Adenosine is used to help restore normal heartbeats in people with certain heart rhythm disorders. Options include: If the patient becomes unstable… start charging! First, let me start with a little bit of evidence. Learn more about Right Ventricular Outflow Tachycardia and Fascicular VT in the ECG Library. 2008 Jan;25(1):15-8. He created the ‘Critically Ill Airway’ course and teaches on numerous courses around the world. 1997 Dec;4(12):1122-8. Otherwise, electrophysiological studies are the definitive diagnostic investigation. . Circulation. I agree – I always try vagal maneuvers first, although I have not had much success with the REVERT technique. Overall, there was no difference in the rate of conversion. 2010 Oct;81 Suppl 1:e93-e174. 2011 Feb 15;123(6):e236. A small minority of fascicular VTs respond to adenosine as do some ischemia-related VTs. 2006. Resuscitation. Patients who were thrilled with diltiazem. Always be prepared. 80(5):523-8. Language may well influence perception. And as I say in the piece, I have seen a handful of patients who have avoided care because they found the adenosine pause so uncomfortable. In Canada, everyone seemed […], Another month and another batch of articles to keep your practice informed. Hypotension seems to be more common with verapamil than with diltiazem (although I have not seen a head to head comparison). Intravenous amiodarone for the pharmacological termination of haemodynamically-tolerated sustained ventricular tachycardia: is bolus dose amiodarone an appropriate first-line treatment? “One special advantage of the skeptical attitude of mind is that a man is never vexed to find that after all he has been in the wrong.” - William Osler. In the absence of these features, VT or SVT with aberrancy are possible. Acta Paediatr Jpn. And frankly, patients who were scared that if they came back, the next doctor would try adenosine again. (Although, if the patient is sedated, I’m not sure why you would opt for adenosine over electrical cardioversion). There were more adverse events with adenosine (10.8% vs 0.6%, p<0.001, OR 0.15, 95% CI 0.09 to 0.26). Blood pressure did drop in the calcium channel group, but the changes (about 10 mmHg systolic) were minor and likely clinically insignificant. It’s great that your patients aren’t suffering. My name is Dr. Morgenstern. 2011; 18(3):148-52. Patients can experience flushing and headache, both of which are related to vasodilation. Presentation at the 2011 ACEP Scientific Assembly. How does adenosine compare to its primary competitors, the calcium channel blockers? 2006 Mar;47(3):227-9. 2011 Mar-Apr;44(2):217-21. I’m going to get it slowed down for you. #FOAMed Medical Education Resources by LITFL is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License. When I asked about the delay, they all said that they were afraid to come in. These are […], A monthly (ish) summary of the emergency medicine literature, Agree! I tend to give 15 mg of diltiazem over 10 minutes. PMID: Tomlinson DR, Cherian P, Betts TR, Bashir Y. You know the drill — if in doubt, treat as VT! Prompt electrical cardioversion is the best answer. Whether VT will be responsive to adenosine cannot be reliably predicted from an ECG. An important caveat: this evidence does not apply to sick patients. an alternative approach, which i have personally used successfully dozens of times is administration of a low dose iv anxiolytic (ie midazolam) … this is very helpful to those with previous negative experiences with the drug, as well as those who are naive to it. I have even had a few patients request that I write them a letter describing the calcium channel blocker treatment plan so that they could request it in the future if/when their SVT recurred. Everywhere I have worked and trained “SVT” is used specifically to refer to AVRT or AVNRT. The calcium channel blockers were better than adenosine at converting patients back to sinus rhythm (98% vs 86.5%, p=0.002, RR 1.13, 95% CI 1.04-1.23). This post is specifically about the management of re-entry tachycardias – the arrythmias that have traditionally been treated with adenosine, but I would argue should be treated with calcium channel blockers as a first line. In 206 adult patients with SVT, 104 were given adenosine (6mg IV push, followed by 12 mg IV push if not successful), 54 were given diltiazem (2.5 mg/min to a max of 50 mg), and 48 were given verapamil (1 mg/min to a max of 20 mg). Doing so may lead to cardioversion directly, or increase the chance that other treatment options are successful. Casey, Great Acad Emerg Med. PMID: Deakin CD, Morrison LJ, Morley PT, Callaway CW, Kerber RE, Kronick SL, Lavonas EJ, Link MS, Neumar RW, Otto CW, Parr M, Shuster M, Sunde K, Peberdy MA, Tang W, Hoek TL, Böttiger BW, Drajer S, Lim SH, Nolan JP; Advanced Life Support Chapter Collaborators. You make an excellent point about priming patients with our language. The recent 2010 ILCOR guidelines (see Deakin et al, 2010) states that: The papers by Hina et al (1996) and Lenk et al (1997) (the latter is a pediatric case series) found that VT did cardiovert with adenosine in over half of their cases! My patients do not want adenosine.
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